NFL Week 1: Betting, Fantasy, Injuries, Matchups and More

The first Sunday of the 2022 NFL season is finally here, and The 33rd Team’s experts have the games covered from every angle.

Will Baker Mayfield excel against his former team? Which new head coaches will thrive in their debuts? What teams will go worst-to-first and which ones made missteps in the offseason?

The 33rd Team’s experts, with more than 1,000 years of NFL experience, break down all of those questions and more, including fantasy, DFS and betting analysis from some of the industry’s best.

Sunday’s Schedule

Dr. Jess Flynn’s Injury Cheat Sheet

Betting Advice

>> Injuries That Will Affect Fantasy, Betting (David Mendelson)

>> Betting Trends That Matter (Chris Farley)

>> Deep Dive into All the Matchups (Ryan Reynolds)

Fantasy Advice

>> The Edge: Game-Changing Tool

>> Week 1 Rankings by Position (Josh Larky)

>> Fantasy World: Week 1 Deep Analysis (Josh Larky)

>> Week 1 Start ‘Em/Sit ‘Em (Matt Hakim)

DFS Advice

Cover 5: Plays to Make in Week 1 (Jordan Vanek)

DFS Cash Games in Week 1 (Kyra Wiaterowski)

High Stakes Advice from a Milly Maker Winner (Matt Hakim)

Ryan Reynolds’ Matchup Breakdowns

Saints @ Falcons (1 p.m.)


Browns @ Panthers (1 p.m.)


“The big storyline to me is will Baker be able to get out of his own way? We know he’s a talented, talented dude, and when you look back at 2020 when he was healthy and then the first game of 2021, he looked really good.” — Chuck Pagano, who breaks down Browns-Panthers

49ers @ Bears (1 p.m.)

“Kyle Shanahan has always done a great job as a play-caller and designing a run and pass game in San Francisco. They love to run the football. Now with a more mobile quarterback in Lance than Jimmy Garoppolo, how much more of the designed quarterback runs are we going to see, in addition to the team’s regular ground game?” — Pagano, who breaks down 49ers-Bears

Steelers @ Bengals (1 p.m.)


Eagles @ Lions (1 p.m.)


Colts @ Texans (1 p.m.)

“I think all the pundits are picking Indy to go down there and win not only that game, but win that division. But I think Houston might be a little bit better than we’re all giving them credit for.” — Pagano, who breaks down Colts-Texans

Patriots @ Dolphins (1 p.m.)


“They struggled in the preseason. [Mac] Jones struggled. It’s well-documented. But I think everybody, including myself, is giving Coach Belichick the benefit of the doubt in this one just because of his resumé and his football IQ and his acumen.” — Pagano, who breaks down Patriots-Dolphins

Ravens @ Jets (1 p.m.)

“Mike Macdonald comes over from Michigan but was with coach John Harbaugh and the Ravens for a number of years before John loaned him to Jim for a year. He knows the organization and what it means to play like a Raven. It will be interesting to see how much that that scheme and that system changes under his direction.” — Pagano, who breaks down Ravens-Jets

Jaguars @ Commanders (1 p.m.)


Chiefs @ Cardinals (4:25 p.m.)


Raiders @ Chargers (4:25 p.m.)


“The Chargers’ defense didn’t play up to coach Brandon Staley’s standard from a year ago. I don’t think they sacked the quarterback at the rate they wanted, so they went out and traded for Khalil Mack … They have studs at all three levels, and they expect great things out of that defense in year two in Staley’s system.” — Pagano, who breaks down Raiders-Chargers

Packers @ Vikings (4:25 p.m.)


Giants @ Titans (4:25 p.m.)

>> Saquon Barkley Ready to Prove Doubters Wrong (Kim Jones)

Buccaneers @ Cowboys (8:20 p.m.)


“A lot of talk about the time Tom Brady missed in training camp. Whatever. He could’ve missed the entire camp in my opinion. Watching him come out against the Colts in the preseason, it looked like he was prepared and locked in for the opening game against the Cowboys.” — Pagano, who breaks down Bucs-Cowboys

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