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11/7/24

10 min read

2024 NFL Week 10: Expert Picks, Predictions For Every Game

Philadelphia Eagles running back Saquon Barkley (26) score on a 19-yard touchdown run during the second quarter against the Jacksonville Jaguars at Lincoln Financial Field.
Philadelphia Eagles running back Saquon Barkley (26) score on a 19-yard touchdown run during the second quarter against the Jacksonville Jaguars at Lincoln Financial Field. Eric Hartline-Imagn Images.

Week 10 should be another great week of NFL action with several big divisional games on top of some awesome AFC-NFC matchups, including the Sunday Night Football contest between the Lions and the Texans.

But who is favored to win this week, and which teams are on upset alert? Here are all of our picks and predictions going into Week 10:

NFL Week 10 Power Rankings

NFL Week 10 Expert Picks

Cincinnati Bengals (4-5) vs. Baltimore Ravens (6-3)

Spread: Ravens -6

Total: 52.5

This was a high-scoring contest just a few weeks ago, with the Baltimore Ravens winning in overtime. But that game was in Cincinnati, and Baltimore is just a different team at home. Joe Burrow and Lamar Jackson are playing like the top two quarterbacks in the NFL this season, but Jackson has much more help around him.

With Tee Higgins (quad) and Orlando Brown (calf) not likely to play on Thursday, that could prove to be too much for the Cincinnati Bengals to overcome. Take the Ravens to win another high-scoring game at home on Thursday Night Football.

Score Prediction: Ravens 31, Bengals 27


New York Giants (2-7) vs. Carolina Panthers (2-7)

Spread: Giants -5

Total: 41.5

This is a “home” game for the Carolina Panthers, but it will be played at Allianz Arena in Munich, Germany. Bryce Young got the start in Week 9 and looked as good as he has in the NFL. The box score numbers don’t necessarily bear that out, but he looked confident and poised for the first time since being the starter at Alabama.

However, the New York Giants' outstanding pass rush could limit his ability to make plays down the field in Week 10. Neither offense inspires a lot of confidence, but the Giants are the more talented team and should get a win overseas.

Score Prediction: Giants 23, Panthers 17


Denver Broncos quarterback Bo Nix runs for a gain in the second quarter against the Baltimore Ravens at M&T Bank Stadium.
Denver Broncos quarterback Bo Nix (10) runs for a gain in the second quarter against the Baltimore Ravens at M&T Bank Stadium. Mitch Stringer-Imagn Images.

Denver Broncos (5-4) vs. Kansas City Chiefs (8-0)

Spread: Chiefs -8

Total: 41.5

If there is one thing we know about this version of the Kansas City Chiefs it's that they don’t really blow any team out. They are 8-0 with their biggest margin of victory being just 13 points against the New Orleans Saints. They just don't have the offensive firepower to score 35+ points, and this is far from a quick-strike offense that we've seen in previous season.

So, while they are the much better team going into this matchup, look for the Denver Broncos defense to get enough stops to keep this game close. Denver can play a ball-control style of offense that should keep the score down. The Chiefs playing an overtime game on Monday Night Football, giving them quite a short week, could be a deciding factor in the spread.

However, the Chiefs should win this game without too much stress, as their defense shouldn't allow more than 17 points to Bo Nix and the Broncos.

Score Prediction: Chiefs 22, Broncos 16


Atlanta Falcons (6-3) vs. New Orleans Saints(2-7)

Spread: Falcons -3

Total: 46.5

Do the New Orleans Saints get a Week 10 bump after firing Dennis Allen? The results have been mixed for interim coaches in the past few years, but this isn’t a terrible spot for the Saints. They are home, and Derek Carr is healthy again. But without Chris Olave and Rashid Shaheed, he won’t have many options to target in the passing game.

Meanwhile, Kirk Cousins has been on fire during the last month, and with Marshon Lattimore gone, the Saints might not have the secondary to hold up in this NFC South matchup. Expect a fairly high-scoring contest here on Sunday, but for the Atlanta Falcons to get the road win and cover the three-point spread.

Score Prediction: Falcons 28, Saints 24


Buffalo Bills (7-2) vs. Indianapolis Colts (4-5)

Spread: Bills -4

Total: 47

This should be an easy win for the Buffalo Bills on paper. They have the better quarterback, and their entire offense is more productive than the Indianapolis Colts. Still, Buffalo being a 4-point road favorite is always a little scary, especially against a quarterback as streaky as Joe Flacco.

If Buffalo can’t create pressure on Flacco, this is a game where he could shine. It also could be a big Jonathan Taylor week, as the Colts might need to rely on him to control the pace of this game. We like the Colts to pull off the home upset here and return to .500 after 10 games.

Score Prediction: Colts 27, Bills 24


Tampa Bay Buccaneers quarterback Baker Mayfield (6) runs out of bounds during the second half against the Tampa Bay Buccaneers at GEHA Field at Arrowhead Stadium
Tampa Bay Buccaneers quarterback Baker Mayfield (6) runs out of bounds during the second half against the Tampa Bay Buccaneers at GEHA Field at Arrowhead Stadium. Jay Biggerstaff-Imagn Images.

San Francisco 49ers (4-4) vs. Tampa Bay Buccaneers (4-5)

Spread: 49ers -6

Total: 48.5

No team in the NFL will have a bigger rest advantage this season than what the San Francisco 49ers will have in Week 10. Coming off a Week 9 bye, the 49ers will take on the Tampa Bay Buccaneers, who just played an overtime game in Kansas City on Monday Night Football.

That means it’s 14 days rest vs. 6, and with Tampa Bay missing several key offensive players, including Mike Evans and Chris Godwin, that could be too much to overcome.

Look for Baker Mayfield to go down swinging in Week 10, but the 49ers will cruise to an easy victory despite being on the road. And with Christian McCaffrey (Achilles) likely coming back, this has a chance to be a blowout win in San Francisco's favor.

Score Prediction: 49ers 28, Buccaneers 20


Pittsburgh Steelers (6-2) vs. Washington Commanders (7-2)

Spread: Commanders -2.5

Total: 46

This might be the best game of the weekend, showing just how far the Pittsburgh Steelers and the Washington Commanders have come this year.

Washington has already surpassed its projected win total, and the Steelers have a full-game lead in the AFC North going into Week 10. This is a tough spot for the young Commanders, as the Steelers are coming off a bye and will be getting several starters back from injury.

It also helps that they have experience playing against Lamar Jackson, a quarterback similar to Jayden Daniels. With Washington’s defense still suspect, the veteran Steelers will steal this game on the road.

Score Prediction: Steelers 24, Commanders 17


New England Patriots (2-7) vs. Chicago Bears (4-4)

Spread: Bears -6.5

Total: 39.5

After a 4-2 start, the Chicago Bears have now dropped two games, including one on the infamous Hail Mary against the Commanders. Can they avoid dropping three straight and get a home win against the New England Patriots?

This is a good matchup for Chicago, as New England’s offense has been better under Drake Maye but not good enough to outscore the Bears. However, the status of both starting tackles for the Bears should be monitored. They missed practice on Wednesday with injuries. Expect another low-scoring game with New England covering, but the Bears getting the home win.

Score Prediction: Bears 21, Patriots 16


Minnesota Vikings (6-2) vs. Jacksonville Jaguars (2-7)

Spread: Vikings -4

Total: 47.5

This certainly feels like a “trap” game for the Minnesota Vikings, who are coming off a big Sunday Night Football win over the Colts. They are going on the road to play an outdoor game against the Jacksonville Jaguars, who have been highly competitive in most games despite their record.

However, Minnesota’s defense does an excellent job of creating pressure on opposing quarterbacks, and Trevor Lawrence has not handled it well at all this season. Don’t expect a blowout win from Minnesota, but look for it to get another win against an AFC South opponent.

Score Prediction: Vikings 28, Jaguars 21


Los Angeles Chargers head coach Jim Harbaugh congratulates running back J.K. Dobbins on his touchdown against the Cleveland Browns during the fourth quarter.
Los Angeles Chargers head coach Jim Harbaugh congratulates running back J.K. Dobbins (27) on his touchdown against the Cleveland Browns during the fourth quarter. Scott Galvin-Imagn Images

Tennessee Titans (2-6) vs. Los Angeles Chargers (5-3)

Spread: Chargers -7.5

Total: 38

The Los Angeles Chargers have the NFL's No. 1 scoring defense, as Jim Harbaugh has brought toughness to Los Angeles. And with the offense starting to click in the passing game, the Chargers finally feel like a threat in the AFC. However, can they avoid slipping up to the Tennessee Titans in Week 10?

Tennessee does have some good playmakers on the offensive side of the ball, and Mason Rudolph has done a fine job filling in for Will Levis. The Chargers should win this game to prove that they can take care of business against the teams they should beat.

Score Prediction: Chargers 24, Titans 13


Philadelphia Eagles (6-2) vs. Dallas Cowboys (3-5)

Spread: Eagles -7.5

Total 41.5

The Dallas Cowboys are expected to get All-Pro EDGE rusher Micah Parsons back this week, but they will be without Dak Prescott for the next several weeks. That is a massive loss for the Cowboys as they look to save their season in Week 10.

Cooper Rush is a fine backup, but he isn’t capable of carrying this team with a poor defense. The Philadelphia Eagles would be wise to lean on the legs of Saquon Barkley, as Dallas has the NFL’s worst run defense. Look for Philadelphia to cruise to an easy divisional win and crush Dallas' playoff hopes once and for all.

Score Prediction: Eagles 31, Cowboys 17


New York Jets (3-6) vs. Arizona Cardinals (5-4)

Spread: Cardinals -1

Total: 46

If the New York Jets want to get back into the playoff race, they have to win this game. Coming off of 10 days of rest, the Jets should be fresh and ready to go. However, the Arizona Cardinals have already topped expectations this season, leading the NFC West going into Week 10.

Kyler Murray can be a difficult quarterback to gameplan against, and New York’s defense could have a hard time slowing down Arizona's run game. This is a tough spot for the Jets despite the rest advantage, given how well Arizona has played during the last month. Take the Cardinals to get another win and eliminate most of the playoff hype surrounding the Jets.

Score Prediction: Cardinals 24, Jets 20


Detroit Lions (7-1) vs. Houston Texans (6-3)

Spread: Lions -3

Total: 50.5

Both the Detroit Lions and the Houston Texans have healthy leads in their respective divisions, but it’s the Lions that are playing like a Super Bowl contender. Detroit didn’t even play all that well against the Packers in Week 9, and it still won convincingly.

Meanwhile, the Texans haven’t protected C.J. Stroud at all this season, and the offense has suffered greatly. Houston’s defense should keep this game close for a while, but look for Detroit’s offense to rip off some big plays and win this game in Houston.

Score Prediction: Lions 27, Texans 20


Los Angeles Rams head coach Sean McVay points to fans while walking to the locker room following an overtime victory against the Seattle Seahawks at Lumen Field.
Los Angeles Rams head coach Sean McVay points to fans while walking to the locker room following an overtime victory against the Seattle Seahawks at Lumen Field. Joe Nicholson-Imagn Images.

Miami Dolphins (2-6) vs. Los Angeles Rams (4-4)

Spread: Rams -2.5

Total: 50.5

The Miami Dolphins have lost their last two games with Tua Tagovailoa under center, but that’s not his fault. He’s played really well, and the offense is functioning at a much higher level. The Dolphins aren’t quite out of the playoff picture in the AFC, but this is a must-win game on Monday Night Football.

Meanwhile, the Los Angeles Rams are right in the thick of things in the NFC West and need a victory to stay competitive with the 49ers, Cardinals, and Seahawks. This should be a high-scoring game, but look for the Dolphins' speed to be too much for the Rams to handle in primetime.

Score Prediction: Dolphins 30, Rams 26


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